Fibrin glue and anal fistulas

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  fibrin glue treatment of anal fistulas is simple, safe, and painless and the injections can be repeated to increase the healing rate without preventing from other eventual following surgical procedures. For these reasons in the past decade this technique became increasingly popular,. Purpose the aim of this study was to evaluate the long-term success and complication rate of fibrin-glue treatment of anal fistulas. Methods patients with an anal fistula presenting to a single surgeon over a three-year period were enrolled in this study. At their first operation, all 48 patients (26-72 years old) underwent anoscopy, biopsy, destruction of the internal gland, and placement. Backgroundaims surgical management of anal fistulas is associated with considerable morbidity, mainly related to anal sphincter injury. However, treatment with fibrin glue is a safe and simple method associated with less discomfort and complications. A prospective trial was conducted at our institute to evaluate the use of fibrin glue (tissucol, baxter, the netherlands) for simple and. Treatment with fibrin glue is currently the only non-surgical option for anal fistulas. It involves the surgeon injecting a glue into the fistula while youre under a general anaesthetic. Purpose the aim of this study was to evaluate the long-term success and complication rate of fibrin-glue treatment of anal fistulas. Methods patients with an anal fistula presenting to a single surgeon over a three-year period were enrolled in this study. At their first operation, all 48 patients (2672 years old) underwent anoscopy, biopsy, destruction of the internal gland, and placement. Conclusions fibrin glue treatment for complex anal fistulas has a low success rate and most recrudescences occurred within three months. However, given the low morbidity and relative simplicity of the procedure, fibrin glue should still be considered as a first-line treatment for patients with complex anal fistulas. Etiology of the anal fistulas was as follows cryptoglandular in 13, crohns disease in four, and miscellaneous in three. Fibrin glue closure of the anal fistula was successful initially in 15 patients (75) and was successful after a second treatment in two additional patients, for an overall fibrin glue fistula closure rate of 85 (17 of 20). Purpose the aim of this study was to evaluate the long-term success and complication rate of fibrin-glue treatment of anal fistulas.   fibrin sealant successfully closed the fistula tract in both patients. After a mean follow-up of 10 months, the overall success rate for fibrin glue closure of anal fistulas was 85. One patient had a recurrent cryptoglandular fistula after two previous fistulotomies and seton placement. Over the past decade, fibrin glue treatment of anal fistulas has become increasingly popular. Fibrin glue is a biological glue which is made of fibrinogen and thrombin along with other clotting factors (aprotonin factor 13 and ca), which when combined, lead to the last step of the clotting mechanism, thus forming a gel like clot 1,2.

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